AFC South
Standings
| Team | W | L | T | WPct | HomeRoad | Div |
Conf | PF | PA | Diff | Streak |
| Indianapolis Colts | 13 | 0 | 0 | 1.000 | 7-0 | 6-0 |
5-0 | 9-0 | 359 | 217 | +142 | Won 13 |
| Jacksonville Jaguars | 7 | 6 | 0 | .538 | 5-2 | 2-4 |
3-2 | 6-3 | 235 | 287 | -52 | Lost 1 |
| Tennessee Titans | 6 | 7 | 0 | .462 | 4-2 | 2-5 |
2-4 | 3-7 | 293 | 323 | -30 | Won 1 |
| Houston Texans | 6 | 7 | 0 | .462 | 3-4 | 3-3 |
1-5 | 4-6 | 311 | 273 | +38 | Won 1 |
Team Stats-Defense
| Total Defense |
| Rnk | Team | Yds | Yds/G |
| 1 | Houston Texans | 4281 | 329.3 |
| 2 | Indianapolis Colts | 4386 | 337.4 |
| 3 | Jacksonville Jaguars | 4504 | 346.5 |
| 4 | Tennessee Titans | 4648 | 357.5 |
| Passing Defense |
| Rnk | Team | Passing Yds | Passing Yds/G |
| 1 | Houston Texans | 2792 | 214.8 |
| 3 | Indianapolis Colts | 2951 | 227.0 |
| 2 | Jacksonville Jaguars | 3113 | 239.5 |
| 4 | Tennessee Titans | 3364 | 258.8 |
| Rushing Defense |
| Rnk | Team | Rushing Yds | Rushing Yds/G |
| 1 | Tennessee Titans | 1284 | 98.8 |
| 3 | Jacksonville Jaguars | 1391 | 107.0 |
| 2 | Indianapolis Colts | 1435 | 110.4 |
| 4 | Houston Texans | 1489 | 114.5 |
Team Stats-Offense
| Total Offense |
| Rnk | Team | Yds | Yds/G |
| 1 | Indianapolis Colts | 4997 | 384.4 |
| 2 | Houston Texans | 4865 | 374.2 |
| 3 | Tennessee Titans | 4685 | 360.4 |
| 4 | Jacksonville Jaguars | 4437 | 341.3. |
| Passing Offense |
| Rnk | Team | Passing Yds | Passing Yds/G |
| 1 | Indianapolis Colts | 3853 | 296.4 |
| 2 | Houston Texans | 3712 | 285.5 |
| 3 | Jacksonville Jaguars | 2776 | 213.5 |
| 4 | Tennessee Titans | 2536 | 195.1 |
| Rushing Offense |
| Rnk | Team | Rushing Yds | Rushing Yds/G |
| 1 | Tennessee Titans | 2149 | 165.3 |
| 2 | Jacksonville Jaguars | 1661 | 127.8 |
| 3 | Houston Texans | 1153 | 88.7 |
| 4 | Indianapolis Colts | 1144 | 88.0 |
Individual Stats-Offense
| Passing |
| Player | Rating | Comp | Att | Pct |
Yds | Yds/G | TD | Int |
| Peyton Manning | 98.9 | 342 | 502 | 68.1 | 3905 |
300 | 29 | 14 |
| Matt Schaub | 98.2 | 324 | 473 | 68.5 | 3814 |
293 | 24 | 13 |
| David Garrard | 84.9 | 250 | 412 | 60.7 | 2987 |
230 | 10 | 6 |
| Vince Young | 90.9 | 113 | 183 | 61.7 | 1383 |
154 | 8 | 5 |
| Rushing |
| Player | Yds | Att | Yds/A | Long |
20+ | TD | Yds/G |
| Chris Johnson | 1626 | 272 | 6.0 | 91 | 20 |
11 | 125.1 |
| Maurice Jones-Drew | 1136 | 251 | 4.5 | 80 | 7 |
14 | 87.4 |
| Joesph Addai | 729 | 197 | 3.7 | 21 | 1 |
9 | 56.1 |
| Steve Slaton | 437 | 131 | 3.3 | 32 | 3 |
3 | 39.7 |
| Recieving |
| Player | Team | Yds | Rec | Avg | TD |
Long | 20+ | Yds/G | Yac |
| Andre Johnson | HOU | 1237 | 81 | 15.3 | 8 | 72 |
16 | 95.2 | 337 |
| Reggie Wayne | IND | 1078 | 87 | 12.4 | 9 | 39 |
17 | 82.9 | 295 |
| Dallas Clark | IND | 902 | 82 | 11.0 | 8 | 80 |
9 | 69.4 | 358 |
| Mike Sims-Walker | JAC | 758 | 53 | 14.3 | 6 | 61 |
11 | 63.2 | 232 |
| Pierre Garcon | IND | 749 | 45 | 16.6 | 4 | 66 |
13 | 57.6 | 210 |
Individual Stats-Defense
| Tackles |
| Position | Player | Team | Tackles |
| LB | Brian Cushing | HOU | 112 |
| LB | Keith Bulluck | TEN | 103 |
| LB | Clint Session | IND | 100 |
| LB | Demeco Ryans | HOU | 98 |
| LB | Stephen Tulloch | TEN | 89 |
| Sacks |
| Position | Player | Team | Sacks |
| DE | Dwight Freeney | IND | 11.5 |
| DE | Robert Mathis | IND | 9.5 |
| DE | Mario Williams | HOU | 8.0 |
| DT | Tony Brown | TEN | 5.0 |
| DE | Jason Jones | TEN | 4.0 |
| Interceptions |
| Position | Player | Team | INT | TD |
| CB | Cortland Finnegan | TEN | 5 | 1 |
| S | Antoine Bethea | IND | 4 | 0 |
| LB | Keith Bulluck | TEN | 3 | 0 |
| CB | Rashean Mathis | JAC | 3 | 0 |
| S | Bernard Pollard | HOU | 3 | 1 |
