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Standings
| Team | W | L | T | WPct | Home | RoadDiv | Conf | PF | PA | Diff | Streak | >|
| Arizona Cardinals | 8 | 5 | 0 | .615 | 3-3 | 5-2 | 3-2 | 6-3 | 306 | 258 | +48 | Lost 1 |
| San Fransisco 49ers | 6 | 7 | 0 | .462 | 5-2 | 1-5 | 4-1 | 5-4 | 269 | 242 | +27 | Won 1 |
| Seattle Seahawks | 5 | 8 | 0 | .385 | 4-2 | 1-6 | 3-3 | 4-6 | 250 | 301 | -51 | Lost 1 |
| St.Louis Rams | 1 | 12 | 0 | .077 | 0-6 | 1-6 | 0-4 | 1-9 | 146 | 361 | -215 | Lost 5 |
| Total Defense | |||
| Rnk | Team | Yds | Yds/G |
| 1 | San Fransisco 49ers | 4402 | 338.6 |
| 2 | Seattle Seahawks | 4643 | 357.2 |
| 3 | Arizona Cardinals | 4678 | 359.8 |
| 4 | St.Louis Rams | 4810 | 370.0 |
| Passing Defense | |||||||||
| Rnk | Team | Passing Yds | Passing Yds/G | ||||||
| 1 | St.Louis Rams | 2896 | 222.8 | ||||||
| 3 | San Fransisco 49ers | 3167 | 243.6 | ||||||
| 2 | Arizona Cardinals | 3232 | 248.6 | ||||||
| 4 | Seattle Seahawks | 3287 | 252.8 | ||||||
| Rushing Defense | |||||||||
| Rnk | Team | Rushing Yds | Rushing Yds/G | ||||||
| 1 | San Fransisco 49ers | 1235 | 95 | ||||||
| 3 | Seattle Seahawks | 1306 | 104.3 | ||||||
| 2 | Arizona Cardinals | 1446 | 111.2 | ||||||
| 4 | St.Louis Rams | 1914 | 147.2 | ||||||
| Total Offense | |||
| Rnk | Team | Yds | Yds/G |
| 1 | Arizona Cardinals | 4576 | 352.0 |
| 2 | Seattle Seahawks | 4089 | 314.5 |
| 3 | St.Louis Rams | 3886 | 298.9 |
| 4 | San Fransisco 49ers | 3752 | 288.6 |
| Passing Offense | |||
| Rnk | Team | Passing Yds | Passing Yds/G |
| 1 | Arizona Cardinals | 3362 | 258.6 |
| 2 | Seattle Seahawks | 2906 | 223.5 |
| 3 | San Fransisco 49ers | 2468 | 189.8 |
| 4 | St.Louis Rams | 2357 | 181.3 |
| Rushing Offense | |||
| Rnk | Team | Rushing Yds | Rushing Yds/G |
| 1 | St.Louis Rams | 1529 | 117.6 |
| 2 | San Fransisco 49ers | 1284 | 98.8 |
| 3 | Arizona Cardinals | 1214 | 93.4 |
| 4 | Seattle Seahawks | 1183 | 91.0 |
| Passing | ||||||||
| Player | Rating | Comp | Att | Pct | Yds | Yds/G | TD | Int |
| Kurt Warner | 93.5 | 289 | 433 | 66.7 | 3181 | 265 | 23 | 13 |
| Matt Hasselback | 83.9 | 232 | 375 | 61.9 | 2400 | 218 | 14 | 8 |
| Alex Smith | 83.3 | 168 | 276 | 60.9 | 1721 | 215 | 15 | 9 |
| Marc Bulger | 70.7 | 40 | 247 | 56.7 | 1469 | 163 | 5 | 6 |
| Rushing | ||||||||
| Player | Yds | Att | Yds/A | Long | 20+ | TD | Yds/G | |
| Steven Jackson | 1279 | 285 | 4.5 | 58 | 9 | 4 | 98.4 | |
| Frank Gore | 835 | 162 | 5.2 | 80 | 9 | 7 | 75.9 | |
| Beanie Wells | 596 | 136 | 4.4 | 29 | 3 | 5 | 45.8 | |
| Tim Hightower | 538 | 121 | 4.4 | 50 | 2 | 6 | 41.4 | |
| Recieving | |||||||||
| Player | Team | Yds | Rec | Avg | TD | Long | 20+ | Yds/G | Yac |
| Larry Fitzgerald | ARI | 991 | 85 | 11.7 | 10 | 34 | 12 | 76.2 | 244 |
| Vernon Davis | SFO | 815 | 66 | 12.3 | 11 | 42 | 12 | 62.7 | 265 |
| Nate Burelson | SEA | 812 | 63 | 12.9 | 3 | 44 | 10 | 62.5 | 246 |
| Anquan Boldin | ARI | 803 | 68 | 11.8 | 4 | 44 | 7 | 66.9 | 291 |
| T.J Houshmandzadeh | SEA | 721 | 65 | 11.1 | 3 | 53 | 8 | 55.5 | 171 |
| Tackles | ||||||
| Position | Player | Team | Tackles | |||
| LB | Patrick Willis | SFO | 132 | |||
| LB | James Laurinaitis | STL | 104 | |||
| LB | Karlos Dansby | ARI | 98 | |||
| S | David Hawthorne | SEA | 93 | |||
| S | Jordan Babineaux | SEA | 92 | |||
| Sacks | ||||||
| Position | Player | Team | Sacks | |||
| DT | Darnell Dockett | ARI | 11.0 | |||
| DE | Leonard Little | STL | 6.5 | |||
| DE | Calais Cole | ARI | 6.0 | |||
| LB | Manny Lawson | SFO | 5.5 | |||
| DE | Bertrand Berry | ARI | 5.0 | |||
| Interceptions | ||||
| Position | Player | Team | INT | TD |
| S | Adrian Wilson | ARI | 4 | 0 |
| S | Antrel Rolle | ARI | 4 | 0 |
| S | James Butler | STL | 3 | 0 |
| S | Dashon Goldson | SFO | 3 | 0 |
| CB | Dominique Rodgers-Cromartie | ARI | 3 | 1 |